Letybo: Wrinkle Reduction

Wrinkle Reduction

Letybo is a neuromodulator used to soften wrinkles and fine lines caused by repeated facial movement. At Skin Anthology, Letybo is placed with precision to smooth expression lines while maintaining natural facial movement. It is commonly used across the forehead, between the brows, and around the eyes. Letybo supports a refreshed, balanced appearance with consistent, predictable results.

How Letybo Works

Letybo is an FDA-approved neuromodulator that temporarily reduces muscle activity in areas prone to dynamic wrinkles. By moderating repetitive movement, existing lines can soften and the formation of deeper wrinkles may be slowed, while natural expression is preserved. Many patients begin to notice changes within several days, with results continuing to settle gradually.

Why We Love Letybo

Softens and Helps Prevent Expression Lines

Letybo reduces muscle activity that contributes to repeated creasing, helping visible lines soften while supporting long-term wrinkle prevention with consistent treatment.

Reliable, Even Results

Letybo is valued for its consistent performance and predictable onset, making it a dependable option for patients seeking steady, well-balanced correction.

Natural, Balanced Outcomes

Dosing and placement are guided by facial anatomy and movement patterns, keeping results smooth and expressive rather than rigid.

Quick and Minimally Invasive

Treatments typically take 15–30 minutes and require little interruption to daily life.

Complements Other Treatments

Letybo pairs well with treatments that support skin texture, tone, and volume, helping results appear cohesive and intentional.

Treatment Expectations and Care

Avoid alcohol for 24 hours

to help reduce bruising risk.

Avoid strenuous exercise for 24 hours

beforehand when possible (increased circulation can contribute to bruising for some.)

Review meds/supplements

If medically appropriate, avoid aspirin, ibuprofen/NSAIDs, and blood-thinning supplements in advance. Never stop prescribed blood thinners or other prescription meds without guidance from your prescribing clinician.

Pause active skincare

Hold retinoids, exfoliating acids, and strong actives for several days prior on the areas being treated to reduce irritation.

Arrive with clean skin when possible

Come with minimal makeup around planned injection sites.

Share your history

Tell us about allergies, medical conditions, neuromuscular conditions, pregnancy/breastfeeding status, current medications and supplements, prior toxin/filler history, and any recent vaccines or planned procedures so we can time treatment appropriately.

Appointment length

Most neuromodulator treatments are completed within 15–30 minutes, depending on the areas treated and individual anatomy.

Injection technique

The product is placed using ultra-fine needles into carefully selected muscles based on facial movement patterns and treatment goals.+

Sensation

Most patients experience minimal discomfort, often described as brief pressure or a quick pinch at the injection site.

Customization

Injection placement and dosing are individualized to support balanced, natural-looking results while preserving facial expression.

Clinical environment

Treatments are performed in a medical environment by trained providers using protocols focused on skin health and safety.

Real-time assessment

Your provider may ask you to make facial expressions during treatment to ensure accurate placement and appropriate dosing.

Avoid contact

Do not touch, rub, massage, or apply makeup to treated areas for at least one hour after treatment.

Stay upright

Remain upright and avoid bending forward, lying flat, or strenuous activity for four hours.

Limit heat & circulation

Avoid alcohol, saunas, hot tubs, intense exercise, and prolonged sun exposure for 24 hours, as increased circulation may increase bruising or swelling.

Normal responses

Mild redness, swelling, or bruising at injection sites may occur and typically resolves within several days.

Results timeline

Initial changes may appear within 3–5 days, with full effects visible after two weeks.

Follow-up

If needed, a follow-up or touch-up can be considered after two weeks, once results have fully settled.

Pricing

Letybo is priced per unit. The number of units used is determined by treatment area, muscle activity, and your aesthetic goals. Your provider will review dosing and create a customized plan during your consultation to ensure consistent, natural-looking correction.

Frequently Asked Questions

Daxxify uses innovative peptide technology that extends how long results last— up to six months compared to 3–4 months with Botox or Dysport. This means fewer appointments and longer-lasting smoothness. The treatment itself feels similar, but you may enjoy your results nearly twice as long.

Results typically last about 3–4 months, though longevity varies based on muscle activity, metabolism, and individual response.

Yes. Letybo is placed to soften expression lines while preserving natural facial movement. The goal is a refreshed, balanced appearance.

Injections are quick and performed with a very fine needle. Most patients experience only mild, brief discomfort.

Downtime is minimal. Mild redness, swelling, or bruising at injection sites may occur and typically resolves within a few days. Most patients return to normal activities the same day.

Yes. Letybo can be combined with dermal fillers, microneedling, laser treatments, and skin therapies. When combined, neuromodulators are always performed last.

Maintenance treatments are typically scheduled every 3–4 months, depending on individual response and treatment goals.